have liver issues. Individuals with liver challenges may have an increased hazard of obtaining side effects from using JOURNAVX Also, opioid-induced hyperalgesia—a affliction wherever prolonged opioid use heightens pain sensitivity—has not been observed in preclinical assessments of conolidine. Contrary to NSAIDs, conolidine would not suppress inflammatory mediators like prostaglandins. https://hilaryu849azl7.wikihearsay.com/user